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Review article: Contemporary management of gastrointestinal, pancreatic and hepatic toxicities of immune checkpoint inhibitors
Alimentary Pharmacology & Therapeutics ( IF 7.6 ) Pub Date : 2024-04-08 , DOI: 10.1111/apt.17980
Matthew J. Townsend 1 , Isaac J. Benque 2 , Michael Li 2, 3 , Shilpa Grover 4, 5
Affiliation  

Immune checkpoint inhibitors (ICIs) are effective oncologic agents which frequently cause immune-related adverse events (irAEs) which can impact multiple organ systems. Onco-Gastroenterology is a novel and emerging subspecialty within gastroenterology focused on cancer treatment-related complications. Gastroenterologists must be prepared to identify and manage diverse immune-mediated toxicities including enterocolitis, hepatitis, pancreatitis and other ICI-induced toxicities.

中文翻译:

评论文章:免疫检查点抑制剂胃肠道、胰腺和肝脏毒性的当代管理

免疫检查点抑制剂(ICIs)是有效的肿瘤药物,经常引起免疫相关不良事件(irAE),从而影响多个器官系统。肿瘤胃肠病学是胃肠病学中一个新兴的亚专业,专注于癌症治疗相关的并发症。胃肠病学家必须准备好识别和处理多种免疫介导的毒性,包括小肠结肠炎、肝炎、胰腺炎和其他 ICI 引起的毒性。
更新日期:2024-04-08
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