Millets stand out as a sustainable crop with the potential to address the issues of food insecurity and malnutrition. These small-seeded, drought-resistant cereals have adapted to survive a broad spectrum of abiotic stresses. Researchers are keen on unravelling the regulatory mechanisms that empower millets to withstand environmental adversities. The aim is to leverage these identified genetic determinants from millets for enhancing the stress tolerance of major cereal crops through genetic engineering or breeding. This review sheds light on transcription factors (TFs) that govern diverse abiotic stress responses and play role in conferring tolerance to various abiotic stresses in millets. Specifically, the molecular functions and expression patterns of investigated TFs from various families, including bHLH, bZIP, DREB, HSF, MYB, NAC, NF-Y and WRKY, are comprehensively discussed. It also explores the potential of TFs in developing stress-tolerant crops, presenting a comprehensive discussion on diverse strategies for their integration.

小米作为一种可持续作物脱颖而出，有可能解决粮食不安全和营养不良问题。这些小种子、抗旱谷物已经适应了广泛的非生物胁迫。研究人员热衷于解开使小米能够抵御环境逆境的监管机制。目的是利用这些从小米中确定的遗传决定因素，通过基因工程或育种来增强主要谷类作物的抗逆性。这篇综述揭示了控制多种非生物胁迫反应并在赋予小米对各种非生物胁迫耐受性方面发挥作用的转录因子（TF）。具体来说，全面讨论了来自不同家族（包括 bHLH、bZIP、DREB、HSF、MYB、NAC、NF-Y 和 WRKY）的研究 TF 的分子功能和表达模式。它还探讨了转录因子在开发抗逆作物方面的潜力，并对它们的整合的不同策略进行了全面的讨论。