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Should all patients with polymyalgia rheumatica have a vascular ultrasound assessment?
Annals of the Rheumatic Diseases ( IF 27.4 ) Pub Date : 2024-03-29 , DOI: 10.1136/ard-2024-225650
Sharon Cowley , Patricia Harkins , Colm Kirby , Richard Conway , David J Kane

There is a growing appreciation that both giant cell arteritis (GCA) and polymyalgia rheumatica (PMR) are closely interrelated conditions that have significant overlap in aetiology, clinical characteristics and treatment regimens. Subclinical GCA in PMR is becoming increasingly recognised, and there is evolving evidence that this may be a more aggressive disease phenotype than PMR. Ultrasound (US) lends itself well as a screening tool for GCA in PMR; it is inexpensive, non-invasive, widely available, lacks ionising radiation, may be performed at the bedside and is recommended by EULAR as a first-line investigation for suspected GCA. There is insufficient evidence to currently recommend that all patients with PMR should have a US assessment for vascular involvement. However, as clinical and laboratory parameters alone do not accurately diagnose patients with subclinical GCA, we suggest that vascular US will be increasingly performed by rheumatologists in practice to identify these patients with PMR, preferably as part of larger prospective outcome studies.

中文翻译:

所有风湿性多肌痛患者都应该接受血管超声评估吗?

人们越来越认识到巨细胞动脉炎(GCA)和风湿性多肌痛(PMR)是密切相关的疾病,在病因学、临床特征和治疗方案方面有显着重叠。 PMR 中的亚临床 GCA 越来越受到人们的认可,并且不断有证据表明,这可能是比 PMR 更具侵袭性的疾病表型。超声(美国)非常适合作为 PMR 中 GCA 的筛查工具;它价格便宜、非侵入性、广泛使用、无电离辐射、可以在床边进行,并且被 EULAR 推荐作为疑似 GCA 的一线检查。目前没有足够的证据建议所有 PMR 患者都应接受超声评估血管受累情况。然而,由于仅凭临床和实验室参数并不能准确诊断亚临床 GCA 患者,我们建议风湿病学家在实践中将越来越多地进行血管超声检查,以识别这些患有 PMR 的患者,最好作为更大的前瞻性结果研究的一部分。
更新日期:2024-03-29
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