Eukaryotic transcriptional machinery often shows local enrichment in dynamic clusters at sites of high expression. A study of zebrafish embryos shows that such clusters can fine-tune the timing of zygotic genome activation by sequestering a component required for productive transcription, thus limiting its availability to other genes.

中文翻译：

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转录机构管理紧张的资源

真核转录机制通常在高表达位点的动态簇中表现出局部富集。对斑马鱼胚胎的研究表明，此类簇可以通过隔离生产转录所需的成分来微调合子基因组激活的时间，从而限制其对其他基因的可用性。