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Lipidomes define immune cell identity
Nature Cell Biology ( IF 21.3 ) Pub Date : 2024-04-08 , DOI: 10.1038/s41556-024-01398-8 Kandice R. Levental , Whitney S. Henry
Nature Cell Biology ( IF 21.3 ) Pub Date : 2024-04-08 , DOI: 10.1038/s41556-024-01398-8 Kandice R. Levental , Whitney S. Henry
Diverse, specialized immune cells defend against pathogens and cancer cells. A new study reveals the comprehensive lipid compositions of these cells, with unique lipidomes associated with various immune cell types. They show that cell-specific lipid compositions determine a key functional phenotype: their susceptibility to ferroptosis.
中文翻译:
脂质体定义免疫细胞身份
多样化、专门的免疫细胞可以防御病原体和癌细胞。一项新研究揭示了这些细胞的全面脂质成分,以及与各种免疫细胞类型相关的独特脂质组。他们表明,细胞特异性脂质成分决定了一个关键的功能表型:它们对铁死亡的易感性。
更新日期:2024-04-08
中文翻译:
脂质体定义免疫细胞身份
多样化、专门的免疫细胞可以防御病原体和癌细胞。一项新研究揭示了这些细胞的全面脂质成分,以及与各种免疫细胞类型相关的独特脂质组。他们表明,细胞特异性脂质成分决定了一个关键的功能表型:它们对铁死亡的易感性。