Herein, a visible light‐mediated defluorination reaction to access 1,1‐difluoro‐1,3‐enynes is described. Compared with previous studies, this protocol employs more readily accessible acids as a radical precursor under the redox‐neutral conditions. Moreover, the reaction exhibits high compatibility with diverse primary, secondary and tertiary acids, especially natural amino acids and drug‐derived acids. Preliminary mechanism investigations reveal that a radical pathway is involved in the catalytic cycle.

中文翻译：

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可见光介导的脱氟反应得到 1,1-二氟-1,3-烯炔

本文描述了一种可见光介导的脱氟反应以获得 1,1-二氟-1,3-烯炔。与以前的研究相比，该方案在氧化还原中性条件下采用更容易获得的酸作为自由基前体。此外，该反应与多种伯酸、仲酸和叔酸，特别是天然氨基酸和药物衍生酸表现出高度相容性。初步机制研究表明催化循环涉及自由基途径。