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Glutamine antagonists may KEAP lung cancer in check
Science Advances ( IF 13.6 ) Pub Date : 2024-03-27 , DOI: 10.1126/sciadv.ado7808
Eliot B. Blatt 1 , Ralph J. DeBerardinis 1, 2
Affiliation  

The glutamine antagonist DRP-104 blocks purine synthesis and combines with checkpoint inhibitors to promote antitumor immunity in KEAP1/NRF2-mutant lung cancers.

中文翻译:

谷氨酰胺拮抗剂可以控制肺癌

谷氨酰胺拮抗剂 DRP-104 可阻断嘌呤合成,并与检查点抑制剂结合,促进 KEAP1/NRF2 突变型肺癌的抗肿瘤免疫。
更新日期:2024-03-27
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