This concept paper summarizes the major contributions to the sulfoxide-directed C−H activation of arenes catalyzed by transition metals. The innovative methodologies developed to activate vicinal and remote sites have spurred a large variety of functionalizations, making available unprecedented molecular structures, including constrained heterocycles. Ultimately, the traceless character of the sulfinyl moiety is highlighted by straightforward functional group interconversion (FGI) after the C−H activation.

中文翻译：

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芳基亚砜：用于催化芳烃 C−H 活化的无痕导向基团

这篇概念论文总结了过渡金属催化的亚砜引导的芳烃 C−H 活化的主要贡献。为激活邻近和远程位点而开发的创新方法刺激了多种功能化，从而提供了前所未有的分子结构，包括受限杂环。最终，CH 激活后直接的官能团互变 (FGI) 突显了亚磺酰基部分的无痕特征。