ImportanceWith exposure to traumatic events and reduced access to mental health care, adolescents of Ukraine during the Russian invasion since February 2022 are at high risk of psychiatric conditions. However, the actual mental health burden of the war has scarcely been documented.ObjectiveTo investigate the prevalence of a positive screen for psychiatric conditions among adolescents amidst the ongoing war in Ukraine as well as their associations with war exposure.Design, Setting, and ParticipantsThis cross-sectional study reports the results from the first wave of the Adolescents of Ukraine During the Russian Invasion cohort, the largest cohort study on Ukrainian adolescents’ mental health during the Russian invasion since 2022. Using self-reported questionnaires, the national-level prevalence of a positive screen for various psychiatric conditions was estimated among adolescents aged 15 years or older attending secondary school in Ukraine in person or online (including those residing abroad but attending Ukrainian secondary school online) and the prevalence among Ukrainian adolescents living abroad due to the war.ExposureSelf-reported exposure to war.Main Outcomes and MeasuresA positive screen for psychiatric conditions. The association between self-reported war exposure and a positive screen for each of the psychiatric conditions was also evaluated.ResultsA total of 8096 Ukrainian adolescents (4988 [61.6%] female) living in Ukraine or abroad were included in the analyses. Based on national-level estimates, 49.6% of the adolescents were directly exposed to war, 32.0% screened positive for moderate or severe depression, 17.9% for moderate or severe anxiety, 35.0% for clinically relevant psychological trauma, 29.5% for eating disorders, and 20.5% for medium risk or higher of substance use disorder. The burden of psychiatric symptoms was similarly large among Ukrainian adolescents living abroad. Adolescents exposed to war were more likely to screen positive for depression (prevalence ratio [PR], 1.39; 95% CI, 1.29-1.50), anxiety (PR, 1.62; 95% CI, 1.45-1.81), clinically relevant psychological trauma (PR, 1.41; 95% CI, 1.32-1.50), eating disorders (PR, 1.21; 95% CI, 1.12-1.32), and substance use disorder (PR, 1.11; 95% CI, 0.98-1.25).Conclusions and RelevanceThe findings of this study suggest that the mental health burden of Ukrainian adolescents amidst the Russian invasion of Ukraine is substantial. Mental health care efforts to alleviate the mental health burden of Ukrainian adolescents are needed.

中文翻译：

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乌克兰战争青少年的心理健康

重要性由于遭受过创伤性事件且获得精神卫生保健的机会减少，自 2022 年 2 月以来俄罗斯入侵期间的乌克兰青少年面临着患精神疾病的高风险。然而，战争造成的实际心理健康负担几乎没有被记录下来。目的调查乌克兰持续战争中青少年精神疾病阳性筛查的流行情况以及它们与战争暴露的关系。设计、设置和参与者这个交叉- 截面研究报告了俄罗斯入侵期间乌克兰青少年第一波队列的结果，这是自 2022 年以来关于俄罗斯入侵期间乌克兰青少年心理健康的最大队列研究。使用自我报告的问卷调查，国家一级的患病率据估计，在乌克兰亲自或在线上中学的 15 岁或以上青少年（包括居住在国外但在线上乌克兰中学的青少年）中，对各种精神疾病的筛查呈阳性，并且由于战争而居住在国外的乌克兰青少年中的患病率也较高。暴露自我报告的战争暴露。主要结果和措施对精神疾病进行积极筛查。还评估了自我报告的战争经历与每种精神疾病的阳性筛查之间的关联。 结果 分析中纳入了居住在乌克兰或国外的总共 8096 名乌克兰青少年（4988 名 [61.6%] 女性）。根据国家层面的估计，49.6%的青少年直接经历过战争，32.0%的青少年筛查出中度或重度抑郁症，17.9%的人患有中度或重度焦虑症，35.0%的人患有临床相关的心理创伤，29.5%的人患有饮食失调， 20.5% 为中等或以上风险的物质使用障碍。生活在国外的乌克兰青少年的精神症状负担也同样严重。经历过战争的青少年更有可能筛查出抑郁症（患病率 [PR]，1.39；95% CI，1.29-1.50）、焦虑症（PR，1.62；95% CI，1.45-1.81）、临床相关心理创伤（ PR，1.41；95% CI，1.32-1.50）、饮食失调（PR，1.21；95% CI，1.12-1.32）和物质使用障碍（PR，1.11；95% CI，0.98-1.25）。结论和相关性这项研究的结果表明，在俄罗斯入侵乌克兰期间，乌克兰青少年的心理健康负担是巨大的。需要采取精神卫生保健措施来减轻乌克兰青少年的心理健康负担。