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Collective antiretroviral protection: new dimensions of community HIV prevention practices at the intersection of U=U and PrEP
The Lancet HIV ( IF 16.1 ) Pub Date : 2024-03-18 , DOI: 10.1016/s2352-3018(24)00034-1
Julien B Brisson , Daniel Grace , Amaya G Perez-Brumer

Collective antiretroviral protection is an evolving sexual health strategy in HIV prevention, used in particular by gay, bisexual, and other men who have sex with men. The strategy involves HIV-negative individuals who engage in condomless sexual activities but, instead of using pre-exposure prophylaxis (PrEP) themselves, choose partners who either have undetectable viral loads or are on PrEP. This biomedical-sorting practice, rooted in the scientific principles of undetectable equals untransmittable (U=U) and PrEP, relies on an indirect protection strategy. Collective antiretroviral protection allows for HIV-negative individuals not on PrEP to benefit from their partner's antiretroviral use, without directly consuming antiretrovirals themselves for HIV prevention, during condomless sex. Empirical research is needed to evaluate the public health implications of this emerging sexual health approach. Research and public health initiatives should adopt a non-stigmatising approach to individuals engaging in collective antiretroviral protection and look beyond individual behaviour to understand the broader community-level effects of this innovative HIV prevention strategy.

中文翻译:

集体抗逆转录病毒保护:U=U 和 PrEP 交叉点上社区艾滋病毒预防实践的新维度

集体抗逆转录病毒保护是预防艾滋病毒的一种不断发展的性健康策略,特别是同性恋、双性恋和其他男男性行为者使用的策略。该策略涉及艾滋病毒阴性个体,他们进行无套性行为,但自己不使用暴露前预防 (PrEP),而是选择病毒载量无法检测到或正在接受暴露前预防 (PrEP) 的伴侣。这种生物医学分选实践植根于不可检测等于不可传播 (U=U) 和 PrEP 的科学原理,依赖于间接保护策略。集体抗逆转录病毒保护允许未接受 PrEP 的艾滋病毒阴性个体在无套性行为期间从其伴侣的抗逆转录病毒药物使用中受益,而无需直接服用抗逆转录病毒药物来预防艾滋病毒。需要进行实证研究来评估这种新兴的性健康方法对公共卫生的影响。研究和公共卫生举措应对参与集体抗逆转录病毒保护的个人采取非污名化的方法,并超越个人行为,了解这一创新艾滋病毒预防策略对社区层面更广泛的影响。
更新日期:2024-03-18
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