Unsymmetrical 1,6-dicarbonyl compounds are useful building blocks in organic synthesis. However, the synthetic methods are limited. Herein we report a three-component one-pot reaction for the synthesis of unsymmetrical 1,6-diketones. This reaction utilizes sulfides as radical precursors and enol ethers as building blocks. It takes advantage of photocatalysis and Lewis acid catalysis. Its synthetic utility was demonstrated in the modification of biorelevant compounds.

中文翻译：

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光催化一锅串联三组分反应合成不对称1,6-二羰基化合物

不对称 1,6-二羰基化合物是有机合成中有用的结构单元。然而，合成方法有限。在此，我们报道了一种用于合成不对称 1,6-二酮的三组分一锅反应。该反应利用硫化物作为自由基前体和烯醇醚作为结构单元。它利用光催化和路易斯酸催化。其合成效用在生物相关化合物的修饰中得到了证明。