Allenes represent a distinctive class of organic molecules characterized by their unique physical and chemical properties. Among them, chiral allenes play a significant role in modern chemistry. They not only serve as pivotal frameworks for natural products and drug molecules but also are essential building blocks in organic synthesis. Over the years, numerous remarkable and efficient methods have been developed for the synthesis of chiral allenes. Notably, the catalytic synthesis of chiral allenes using transition metals in conjunction with chiral ligands has garnered considerable attention. This review paper aims to provide an overview of recent advancements in the synthesis of chiral allenes through asymmetric 1,4‐difunctionalization of 1,3‐enynes, in which two distinct strategies including non‐radical and radical processes are highlighted.

中文翻译：

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通过1,3-烯炔的不对称1,4-双官能化合成手性艾伦烯的最新进展

丙二烯代表一类独特的有机分子，其特征在于其独特的物理和化学性质。其中，手性丙二烯在现代化学中发挥着重要作用。它们不仅是天然产物和药物分子的关键框架，而且是有机合成的重要组成部分。多年来，人们开发了许多出色且有效的方法来合成手性丙二烯。值得注意的是，使用过渡金属与手性配体结合催化合成手性丙二烯已引起相当多的关注。本综述旨在概述通过 1,3-烯炔的不对称 1,4-二官能化合成手性丙二烯的最新进展，其中强调了两种不同的策略，包括非自由基和自由基过程。