Transcriptional coactivators CBP/p300 have emerged as potential targets for cancer therapeutics. This Viewpoint discusses recent results that demonstrate an exceptionally potent and orally efficacious CBP/p300 degrader for the treatment of prostate cancer. This degrader stands out as a promising new candidate for cancer therapy and deserves further research.

中文翻译：

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CBP/p300 Degrader：治疗前列腺癌及其他癌症的有前途的治疗策略

转录共激活剂 CBP/p300 已成为癌症治疗的潜在靶标。本观点讨论了最近的结果，这些结果证明了一种非常有效且口服有效的 CBP/p300 降解剂，可用于治疗前列腺癌。这种降解剂是一种有前途的癌症治疗新候选者，值得进一步研究。