What Stirs Beneath. Understanding protein–specific interactomes, or localization, is crucial for decoding protein function. New biotinylation methods can do just that even in live organisms. However, these methods have some limitations as they are intrinsically unable to directly probe function. Here new methods that can investigate locale–specific reactivity, are discussed, opening routes to locale–specific perturbation of function.

中文翻译：

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爬入皮肤以了解背景蛋白质-蛋白质关联和定位：转基因活体模型生物的功能研究

下面是什么在搅动。了解蛋白质特异性相互作用组或定位对于解码蛋白质功能至关重要。即使在活体生物体中，新的生物素化方法也能做到这一点。然而，这些方法有一些局限性，因为它们本质上无法直接探测功能。这里讨论了可以研究特定区域反应性的新方法，开辟了区域特定功能扰动的途径。