Rhodium-Catalyzed Enantioselective Cyclization of 2-Allenylbenzoxazoles,Organic Letters

当前位置： X-MOL 学术 › Org. Lett. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Rhodium-Catalyzed Enantioselective Cyclization of 2-Allenylbenzoxazoles
Organic Letters ( IF 4.9 ) Pub Date : 2024-03-20 , DOI: 10.1021/acs.orglett.4c00526
Antonia Becker ₁ , Felix Bauer ₁ , Bernhard Breit ₁

Affiliation

The enantioselective rhodium-catalyzed cyclization of 2-allenylbenzoxazoles to the corresponding vinyl-functionalized, fused heterocyclic structures is reported. The presented method offers several advantages, including the use of low catalyst loadings, commercially available catalyst precursors, and mild reaction conditions. Due to its broad scope, scalability, and valuable products, we consider this methodology to be a useful tool for the construction of benzoxazole-containing building blocks.

中文翻译：

铑催化的 2-烯基苯并恶唑的对映选择性环化

报道了 2-烯基苯并恶唑对映选择性铑催化环化成相应的乙烯基官能化稠合杂环结构。该方法具有多种优点，包括使用低催化剂负载量、市售催化剂前体和温和的反应条件。由于其广泛的范围、可扩展性和有价值的产品，我们认为这种方法是构建含苯并恶唑结构单元的有用工具。

更新日期：2024-03-20

点击分享查看原文

点击收藏

阅读更多本刊最新论文本刊介绍/投稿指南11