Per- and polyfluoroalkyl substances (PFAS) are ubiquitously detected in the environment, raising concerns about human exposure. The assessment of individual exposure to PFAS has been limited due to the lack of specialized sampling tools. Personal wearable samplers, including silicone wristbands, have been used for PFAS exposure assessment. However, translating data into human exposure has been challenging due to the lack of chemical sampling rates by those samplers. We developed and evaluated a personal air wearable sampler (PAWS) using sorbent-impregnated polyurethane foam for its ability to capture diverse PFAS. Simultaneously, we deployed silicone wristbands for comparison. Our results showed that the PAWS effectively captured both ionic and neutral PFAS, while silicone wristbands had relatively limited capacity for perfluorocarboxylic acids (PFCAs). Our observations suggest silicone wristbands may collect polyfluoroalkyl phosphoric acid diesters (diPAPs) through dermal contact, although further investigation is necessary. PFAS concentrations detected in the PAWS can be converted into concentrations in air by using previously established sampling rates, facilitating quantitative inhalation exposure assessment. Smoking status was found to be associated with high diPAP levels in both PAWS and silicone wristbands, although further validation is needed. The PAWS is a promising technology for application in personal exposure assessment for structurally diverse chemicals.

中文翻译：

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用于全氟烷基和多氟烷基物质暴露评估的个人可穿戴采样器

全氟烷基物质和多氟烷基物质 (PFAS) 在环境中随处可见，引起了人们对人类接触的担忧。由于缺乏专门的采样工具，对个人接触 PFAS 的评估受到限制。个人可穿戴采样器，包括硅胶腕带，已用于 PFAS 暴露评估。然而，由于这些采样器缺乏化学采样率，将数据转化为人体暴露量一直具有挑战性。我们使用吸附剂浸渍的聚氨酯泡沫开发并评估了个人空气可穿戴采样器 (PAWS)，其捕获多种 PFAS 的能力。同时，我们还使用了硅胶腕带进行对比。我们的结果表明，PAWS 可有效捕获离子型和中性 PFAS，而硅胶腕带对全氟羧酸 (PFCA) 的捕获能力相对有限。我们的观察表明，硅胶腕带可能会通过皮肤接触收集多氟烷基磷酸二酯 (diPAP)，但还需要进一步研究。 PAWS 中检测到的 PFAS 浓度可以使用之前建立的采样率转换为空气中的浓度，从而促进定量吸入暴露评估。研究发现，吸烟状况与 PAWS 和硅胶腕带中的高 diPAP 水平有关，但还需要进一步验证。 PAWS 是一项很有前途的技术，可用于结构多样的化学品的个人暴露评估。