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cGAS meets its demise in the nucleus
Nature Immunology ( IF 27.7 ) Pub Date : 2024-03-21 , DOI: 10.1038/s41590-024-01794-0
Calvin Jon A Leonen 1 , Hironori Funabiki 1
Affiliation  

DNA sensing for the purposes of innate immunity is tricky when the DNA sensor can easily become stuck on chromosomes during cell division. The mechanism by which the trapped DNA sensor is degraded — and how this process can be balanced with added immune protection — is now reported.

中文翻译:


cGAS 在细胞核中消亡



当 DNA 传感器在细胞分裂过程中很容易卡在染色体上时,用于先天免疫的 DNA 传感就很棘手。现在报道了被捕获的 DNA 传感器降解的机制,以及如何通过增加免疫保护来平衡这一过程。
更新日期:2024-03-21
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