BURP-domain proteins belong to an emerging class of autocatalytic copper-containing proteins that modify themselves after synthesis. Now, a report explains how their structure and metal coordination sphere control the installation of crosslinks within the core peptide, and shows how nature leverages mechanistic paradigms to create diversity.

中文翻译：

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用铜进行撕裂和缝合

BURP 结构域蛋白属于一类新兴的自催化含铜蛋白，可在合成后进行自我修饰。现在，一份报告解释了它们的结构和金属配位球如何控制核心肽内交联的安装，并展示了大自然如何利用机械范式来创造多样性。