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Natural distribution, structures, synthesis, and bioactivity of hasubanan alkaloids
ChemMedChem ( IF 3.4 ) Pub Date : 2024-03-20 , DOI: 10.1002/cmdc.202300721
Yingjie Wang 1 , Fuxin Sun 1 , Yapeng Liang 1 , Di Zhou 1 , Gang Chen 1 , Ning Li 2
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Hasubanan alkaloids represent a distinct class of alkaloids bearing a structural resemblance to morphine, predominantly found in herbals of the Stephania genus. Their intriguing molecular architecture and potential analgesic properties have captured the interest of medicinal chemists worldwide. This review meticulously examines the natural distribution, structural characteristics, biosynthetic pathways, synthetic methodologies, and biological activities of hasubanans.

中文翻译:

哈苏巴南生物碱的自然分布、结构、合成和生物活性

哈苏巴南生物碱是一类独特的生物碱,其结构与吗啡相似,主要存在于千金藤属草药中。它们有趣的分子结构和潜在的镇痛特性引起了全世界药物化学家的兴趣。这篇综述仔细研究了哈苏巴南的自然分布、结构特征、生物合成途径、合成方法和生物活性。
更新日期:2024-03-20
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