Engineered regulatory T (T_reg) cells have emerged as precision therapeutics aimed at inducing immune tolerance while reducing the risks associated with generalized immunosuppression. This Viewpoint highlights the opportunities and challenges for engineered T_reg cell therapies in treating autoimmune and other inflammatory diseases.

中文翻译：

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利用调节性 T 细胞建立免疫耐受

工程化调节性 T (T _reg ) 细胞已成为精准疗法，旨在诱导免疫耐受，同时降低与全身免疫抑制相关的风险。_{这一观点强调了工程化 T reg}细胞疗法在治疗自身免疫性疾病和其他炎症性疾病方面的机遇和挑战。