A new and feasible synthetic method for ureas, carbamates and thiocarbamate from hydroxamic acid and Tf₂O via Lossen rearrangement has been developed. The use of Tf₂O was chemoselective with hydroxamate group with broad substrate applicability and good functional group tolerance. Further pathway of the mechanism was analysed through computational studies.

中文翻译：

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Tf2O 促进通过 Lossen 重排合成尿素、氨基甲酸酯和硫代氨基甲酸酯：机理见解

开发了一种新的、可行的由异羟肟酸和Tf ₂ O通过Lossen重排合成脲、氨基甲酸酯和硫代氨基甲酸酯的方法。 Tf ₂ O的使用对异羟肟酸基团具有化学选择性，具有广泛的底物适用性和良好的官能团耐受性。通过计算研究分析了该机制的进一步途径。