A general and efficient synthetic protocol was developed to synthesize highly functionalized 3‐furylmethyl chromones from enynones and o‐hydroxyphenyl enaminones via silver‐catalyzed cascade bis‐heteroannulation reaction. This strategy features broad substrate scope broad and good functional group tolerance. Furthermore, the 3‐furylmethyl chromone skeleton shows the potential synthetic application value through further gram‐scale synthesis and derivatization.

中文翻译：

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银催化烯炔酮和邻羟基苯基烯胺酮的级联双杂环化反应：获得高度功能化的 3-呋喃甲基色酮

开发了一种通用且有效的合成方案，通过银催化级联双杂环化反应，从烯酮和邻羟基苯基烯胺酮合成高度功能化的3-呋喃甲基色酮。该策略具有底物范围广、官能团耐受性好的特点。此外，3-呋喃甲基色酮骨架通过进一步的克级合成和衍生化显示出潜在的合成应用价值。