An enantioselective deoxygenative functionalization of secondary amides with vinylpridines is developed by merging relay iridium catalysis and cooperative photoredox-chiral Brønsted acid catalysis, affording a series of valuable chiral amines in moderate to good yields with good enantioselectivities. The intriguing multiple catalytic system invoking triple-catalysis was found to be the key to the success of the current reactions, which may stimulate further development of catalytic methodologies for asymmetric deoxygenative transformations of amides.

中文翻译：

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三重铱-光氧化还原-手性磷酸体系实现仲酰胺与乙烯基吡啶的不对称脱氧官能化

通过合并中继铱催化和协同光氧化还原-手性布朗斯台德酸催化，开发了仲酰胺与乙烯基吡啶的对映选择性脱氧官能化，以中等至良好的收率和良好的对映选择性提供了一系列有价值的手性胺。人们发现，涉及三重催化的有趣的多重催化系统是当前反应成功的关键，这可能会刺激酰胺不对称脱氧转化催化方法的进一步发展。