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Hypertension facilitates age-related diseases. ~ Is hypertension associated with a wide variety of diseases?~
Hypertension Research ( IF 5.4 ) Pub Date : 2024-03-15 , DOI: 10.1038/s41440-024-01642-6
Masaki Mogi , Yasuhito Ikegawa , Shunsuke Haga , Satoshi Hoshide , Kazuomi Kario

Hypertension, a disease whose prevalence increases with age, induces pathological conditions of ischemic vascular disorders such as cerebral infarction and myocardial infarction due to accelerated arteriosclerosis and circulatory insufficiency of small arteries and sometimes causes hemorrhagic conditions such as cerebral hemorrhage and ruptured aortic aneurysm. On the other hand, as it is said that aging starts with the blood vessels, impaired blood flow associated with vascular aging is the basis for the development of many pathological conditions, and ischemic changes in target organs associated with vascular disorders result in tissue dysfunction and degeneration, inducing organ hypofunction and dysfunction. Therefore, we hypothesized that hypertension is associated with all age-related vascular diseases, and attempted to review the relationship between hypertension and diseases for which a relationship has not been previously well reported. Following our review, we hope that a collaborative effort to unravel age-related diseases from the perspective of hypertension will be undertaken together with experts in various specialties regarding the relationship of hypertension to all pathological conditions.



中文翻译:

高血压会促进与年龄相关的疾病。~ 高血压与多种疾病有关吗?~

高血压是一种随着年龄的增长而患病率增加的疾病,由于动脉硬化加速和小动脉循环不足,诱发脑梗塞、心肌梗塞等缺血性血管疾病的病理状态,有时还会引起脑出血、主动脉瘤破裂等出血性疾病。另一方面,据说衰老始于血管,与血管衰老相关的血流受损是许多病理状况发展的基础,而与血管疾病相关的靶器官的缺血性变化会导致组织功能障碍和退化,导致器官机能减退和功能障碍。因此,我们假设高血压与所有与年龄相关的血管疾病有关,并试图回顾高血压与先前尚未充分报道的疾病之间的关系。经过我们的审查,我们希望与各专业的专家一起合作,从高血压的角度阐明与年龄相关的疾病,了解高血压与所有病理状况的关系。

更新日期:2024-03-15
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