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Harnessing regulatory T cells to establish immune tolerance
Science Translational Medicine ( IF 17.1 ) Pub Date : 2024-03-13 , DOI: 10.1126/scitranslmed.adm8859 Patrick Ho 1 , Ellen Cahir-McFarland 2 , Jason D. Fontenot 3 , Tracey Lodie 4 , Adel Nada 5 , Qizhi Tang 1, 6, 7, 8 , Laurence A. Turka 9 , Jeffrey A. Bluestone 10
Science Translational Medicine ( IF 17.1 ) Pub Date : 2024-03-13 , DOI: 10.1126/scitranslmed.adm8859 Patrick Ho 1 , Ellen Cahir-McFarland 2 , Jason D. Fontenot 3 , Tracey Lodie 4 , Adel Nada 5 , Qizhi Tang 1, 6, 7, 8 , Laurence A. Turka 9 , Jeffrey A. Bluestone 10
Affiliation
Engineered regulatory T (T reg ) cells have emerged as precision therapeutics aimed at inducing immune tolerance while reducing the risks associated with generalized immunosuppression. This Viewpoint highlights the opportunities and challenges for engineered T reg cell therapies in treating autoimmune and other inflammatory diseases.
中文翻译:
利用调节性 T 细胞建立免疫耐受
工程监管 T (T注册 )细胞已成为精准疗法,旨在诱导免疫耐受,同时降低与全身免疫抑制相关的风险。这一观点强调了工程 T 的机遇和挑战注册 细胞疗法治疗自身免疫性疾病和其他炎症性疾病。
更新日期:2024-03-13
中文翻译:
利用调节性 T 细胞建立免疫耐受
工程监管 T (T