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CinNapht AIE(E)gens for selective imaging of lipid droplets
Organic & Biomolecular Chemistry ( IF 3.2 ) Pub Date : 2024-03-12 , DOI: 10.1039/d4ob00247d
Eléonore Tacke 1 , Minh-Duc Hoang 1 , Lilian Estaque 2 , Philippe Durand 1 , Grégory Pieters 2 , Arnaud Chevalier 1
Affiliation  

This article describes the synthesis and photophysical properties of Aggregation-Induced Emission (enhancement) luminogens derivated from CinNaphts dyes. These fluorophores can be obtained in good yields in a single SNAr step of a fluorinated CinNapht derivative by incorporating hindered aromatic amines. They exhibit AIE(E) behavior associated with solid-state fluorescence covering an emission range from 563 to 722 nm. One carbazole derivative demonstrates a remarkable efficiency in imaging lipid droplets in living cells through an original photophysical mechanism.

中文翻译:

CinNapht AIE(E)gens 用于脂滴选择性成像

本文描述了源自 CinNaphts 染料的聚集诱导发射(增强)发光体的合成和光物理性质。通过掺入受阻芳香胺,可以在氟化 CinNapht 衍生物的单个 SNAr 步骤中以良好的产率获得这些荧光团。它们表现出与固态荧光相关的 AIE(E) 行为,发射范围为 563 至 722 nm。一种咔唑衍生物通过原始的光物理机制在活细胞中的脂滴成像方面表现出显着的效率。
更新日期:2024-03-12
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