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MEGA CRISPR rejuvenates exhausted CAR T cells
Nature Medicine ( IF 82.9 ) Pub Date : 2024-03-11 , DOI: 10.1038/d41591-024-00014-4
Karen O’Leary

MEGA is a new CRISPR-based RNA-editing platform with the ability to enhance the fitness of CAR T cells; it may also overcome certain limitations of conventional DNA-targeting CRISPR–Cas9 systems.

中文翻译:

MEGA CRISPR 使耗尽的 CAR T 细胞恢复活力

MEGA是一种基于CRISPR的新型RNA编辑平台,能够增强CAR T细胞的适应性;它还可以克服传统 DNA 靶向 CRISPR-Cas9 系统的某些局限性。
更新日期:2024-03-12
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