Abdominal distention results from abdominophrenic dyssynergia (diaphragmatic contraction and abdominal wall relaxation) in patients with disorders of the gut-brain interaction. This study aimed to validate a simple biofeedback procedure, guided by abdominothoracic wall motion, for treating abdominal distension. In this randomized, parallel, placebo-controlled trial, 42 consecutive patients (36 women and 6 men; age, 17–64 years) with meal-triggered visible abdominal distension were recruited. Recordings of abdominal and thoracic wall motion were obtained using inductance plethysmography via adaptable belts. The signal was shown to patients in the biofeedback group, who were taught to mobilize the diaphragm. In contrast, the signal was not shown to the patients in the placebo group, who were given a placebo capsule. Three sessions were performed over a 4-week intervention period, with instructions to perform exercises (biofeedback group) or to take placebo three times a day (control group) at home. Outcomes were assessed through a) response to an offending meal (changes in abdominothoracic electromyographic activity and girth), and b) clinical symptoms measured using daily scales for 7 days. Patients in the biofeedback group (n=19) a) learned to correct abdominophrenic dyssynergia triggered by the offending meal (intercostal activity decreased by 82±10%, anterior wall activity increased by 97±6%, and the increase in girth was 108±4% smaller) and b) experienced improved clinical symptoms (abdominal distension scores decreased by 66±5%). These effects were not observed in the placebo group (all p<0.002). Abdominothoracic wall movements serve as an effective biofeedback signal for correcting abdominophrenic dyssynergia and abdominal distention in patients with disorders of the gut-brain interaction.

中文翻译：

---

胸腹壁运动引导的腹胀生物反馈治疗：随机安慰剂对照试验

肠-脑相互作用障碍患者的腹膈协同失调（膈肌收缩和腹壁松弛）会导致腹胀。本研究旨在验证一种由腹胸壁运动引导的简单生物反馈程序用于治疗腹胀。在这项随机、平行、安慰剂对照试验中，连续招募了 42 名因进餐而出现明显腹胀的患者（36 名女性和 6 名男性；年龄 17-64 岁）。使用感应体积描记法通过适应性带获得腹部和胸部壁运动的记录。该信号被显示给生物反馈组的患者，并教导他们活动膈肌。相比之下，服用安慰剂胶囊的安慰剂组患者则没有看到信号。在 4 周的干预期内进行了 3 次治疗，并指导在家进行锻炼（生物反馈组）或每天服用 3 次安慰剂（对照组）。通过以下方式评估结果：a) 对违规膳食的反应（腹胸肌电图活动和周长的变化），b) 使用每日量表测量的临床症状，持续 7 天。生物反馈组患者 (n=19) a) 学会纠正由不良膳食引发的腹膈协同失调（肋间活动减少 82±10%，前壁活动增加 97±6%，周长增加 108±缩小 4%) 和 b) 临床症状得到改善（腹胀评分下降 66±5%）。在安慰剂组中没有观察到这些效应（所有 p<0.002）。腹胸壁运动可作为有效的生物反馈信号，用于纠正肠-脑相互作用障碍患者的腹膈协同失调和腹胀。