Cardiovascular disease (CVD) is a global health concern. Circadian medicine improves cardiovascular care by aligning treatments with our body’s daily rhythms and their underlying cellular circadian mechanisms. Time-based therapies, or chronotherapies, show special promise in clinical cardiology. They optimize treatment schedules for better outcomes with fewer side effects by recognizing the profound influence of rhythmic body cycles. In this review, we focus on three chronotherapy areas (medication, light, and meal timing) with potential to enhance cardiovascular care. We also highlight pioneering research in the new field of rest, the gut microbiome, novel chronotherapies for hypertension, pain management, and small molecules that target the circadian mechanism.

中文翻译：

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开拓心血管健康昼夜节律医学计时疗法的新领域

心血管疾病（CVD）是一个全球性的健康问题。昼夜节律医学通过使治疗与我们身体的日常节律及其潜在的细胞昼夜节律机制保持一致来改善心血管护理。基于时间的疗法或时间疗法在临床心脏病学中显示出特殊的前景。他们认识到节律性身体周期的深远影响，优化治疗方案，以获得更好的结果和更少的副作用。在这篇综述中，我们重点关注三个具有增强心血管护理潜力的时间疗法领域（药物、光照和进餐时间）。我们还重点介绍了休息新领域、肠道微生物组、高血压的新型时间疗法、疼痛管理和针对昼夜节律机制的小分子的开创性研究。