Since little is known about the comparison of the biotoxic effects of heavy metals exposure on biochemical and hematological parameters in miners and non-miners, the current study aimed to compare the effects of arsenic (As), lead (Pb), and copper (Cu) in both groups. Demographic information and blood samples were collected from all participants and measures of As, Pb and Cu were obtained using Atomic Absorption Spectrophotometry. As and Pb mean concentrations in miners and Cu concentration were greater in non-miners. Miners also showed significantly higher level of RBC, HBG and HCT. In the adjusted model, cholesterol showed a positively association with Pb and Cu levels. Triglycerides, GGT, ALP, WBC and PLT positively and HDL-cholesterol negatively were associated with Cu. Creatinine was negatively associated with group variable. In conclusion, miners' high blood heavy metals concentrations can impact biochemical and hematological indices. These observations make monitoring of heavy metals necessary in miners.

中文翻译：

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重金属暴露对矿工和非矿工的生物毒性影响

由于对于矿工和非矿工重金属暴露对生化和血液学参数的生物毒性影响的比较知之甚少，本研究旨在比较砷 (As)、铅 (Pb) 和铜 (Cu) 的影响。 ）在两组中。从所有参与者收集人口统计信息和血液样本，并使用原子吸收分光光度法获得砷、铅和铜的测量值。矿工中砷和铅的平均浓度以及非矿工中铜的浓度较高。矿工的红细胞、HBG 和 HCT 水平也显着升高。在调整后的模型中，胆固醇与铅和铜水平呈正相关。甘油三酯、GGT、ALP、WBC 和 PLT 与 Cu 呈正相关，HDL-胆固醇呈负相关。肌酐与组变量呈负相关。总之，矿工血液重金属浓度较高会影响生化和血液学指标。这些观察结果使得对矿工的重金属监测变得必要。