Stretchable sweat sensors are promising technology that can acquire biomolecular insights for health and fitness monitoring by intimate integration with the body. However, current sensors often require microfabricated microfluidic channels to control sweat flow during lab-on-body analysis, which makes effective and affordable sweat sampling a significant practical challenge. Here, we present stretchable and sweat-wicking patches that utilize bioinspired smart wettable membranes for the on-demand manipulation of sweat flow. In a scalable process, the membrane is created by stacking hydrophobic elastomer nanofibers onto soft microfoams with predefined two-dimensional superhydrophobic and superhydrophilic patterns. The engineered heterogeneous wettability distribution allows these porous membranes to achieve enhanced extraction and selective collection of sweat in embedded assays. Despite the simplified architecture, the color reactions between sweat and chemical indicators are inhibited from directly contacting the skin to achieve a largely improved operation safety. The sensing patches can simultaneously quantify pH, urea, and calcium in sweat through digital colorimetric analysis with smartphone images. The construction with all compliant materials renders these patches soft and stretchy to achieve conformal attachment to the skin. Successfully analyzing sweat compositions after physical exercises illustrates the practical suitability of these skin-attachable sensors for health tracking and point-of-care diagnosis.

中文翻译：

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用于汗液生物标记物皮肤附着比色分析的可拉伸吸汗贴片

可拉伸汗液传感器是一种很有前景的技术，它可以通过与身体的紧密结合来获取生物分子见解，从而进行健康和健身监测。然而，当前的传感器通常需要微加工的微流体通道来控制人体实验室分析过程中的汗液流动，这使得有效且经济实惠的汗液采样成为重大的实际挑战。在这里，我们展示了可拉伸和排汗的贴片，它们利用仿生智能可湿膜来按需控制汗液流动。在可扩展的过程中，通过将疏水性弹性体纳米纤维堆叠到具有预定义的二维超疏水和超亲水图案的软微泡沫上来创建膜。工程化的异质润湿性分布使这些多孔膜能够在嵌入式测定中实现增强的汗液提取和选择性收集。尽管简化了架构，但汗液和化学指示剂之间的颜色反应被抑制，不会直接接触皮肤，从而大大提高了操作安全性。传感贴片可以通过智能手机图像的数字比色分析同时量化汗液中的 pH 值、尿素和钙。采用所有合规材料的结构使这些贴片柔软且有弹性，以实现与皮肤的保形附着。体育锻炼后的汗液成分的成功分析说明了这些贴在皮肤上的传感器对于健康跟踪和护理点诊断的实际适用性。