Kir4.1 potassium channels expressed in astroglial cells critically regulate extracellular potassium concentration in the brain. A new study reports that blocking the flow of potassium ions into astrocytes by inhibiting Kir4.1 induces rapid-onset antidepressive effects in rodents.

中文翻译：

---

大坝抗抑郁药

星形胶质细胞中表达的 Kir4.1 钾通道关键调节大脑中细胞外钾的浓度。一项新的研究报告称，通过抑制 Kir4.1 来阻止钾离子流入星形胶质细胞，可在啮齿类动物中产生快速起效的抗抑郁作用。