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Unveiling the antitumor function of ID3 in liver macrophages
Nature Immunology ( IF 30.5 ) Pub Date : 2024-03-01 , DOI: 10.1038/s41590-024-01761-9
Anne-Gaëlle Goubet , Mikaël J. Pittet

A landmark study reveals how Kupffer cells, resident macrophages of the liver, can promote antitumor immunity. Central to this function is ID3, a Kupffer cell lineage-determining factor. The findings provide new insights into cancer therapy.

中文翻译:

揭示肝巨噬细胞中 ID3 的抗肿瘤功能

一项具有里程碑意义的研究揭示了库普弗细胞(肝脏的常驻巨噬细胞)如何促进抗肿瘤免疫。该功能的核心是 ID3,它是库普弗细胞谱系决定因子。这些发现为癌症治疗提供了新的见解。
更新日期:2024-03-02
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