Objective

To evaluate factors associated with borderline/clinical range Child Behavior Checklist (CBCL) scores in opioid-exposed children.

Study design

Retrospective study of 94 children with prenatal opioid exposure evaluated with the CBCL at age 2 years.

Results

Twenty-eight children (30%) had borderline/clinical findings on the CBCL, with 27% scoring borderline/clinical for Externalizing Problems. In the multivariable model, lower Bayley-III motor scores and discharge home with mother with safety plan were associated with borderline/clinical Externalizing Problems. Medication treatment for neonatal opioid withdrawal syndrome (NOWS) was associated with normal Externalizing Problems scores. Treatment with clonidine or phenobarbital was associated with scores in the normal range in all broadband CBCL measures.

Conclusion

Specific factors are associated with behavioral and emotional challenges measured by borderline/clinical CBCL scores among opioid-exposed children.

中文翻译：

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产前阿片类药物暴露儿童 2 岁时的神经行为问题

客观的

评估与阿片类药物暴露儿童的临界/临床范围儿童行为检查表 (CBCL) 评分相关的因素。

学习规划

对 94 名产前阿片类药物暴露儿童在 2 岁时使用 CBCL 进行评估的回顾性研究。

结果

28 名儿童 (30%) 在 CBCL 中出现边缘/临床结果，其中 27% 的外化问题得分为边缘/临床。在多变量模型中，较低的 Bayley-III 运动评分和带着安全计划的母亲出院与边缘/临床外化问题相关。新生儿阿片类药物戒断综合征 (NOWS) 的药物治疗与正常的外化问题评分相关。使用可乐定或苯巴比妥治疗与所有宽带 CBCL 测量中的分数均处于正常范围相关。

结论

特定因素与阿片类药物暴露儿童的行为和情绪挑战相关，这些挑战是通过边缘/临床 CBCL 评分来衡量的。