This review highlights the transformative impact of microfluidic technology on personalized drug delivery. Microfluidics addresses issues in traditional drug synthesis, providing precise control and scalability in nanoparticle fabrication, and microfluidic platforms show high potential for versatility, offering patient-specific dosing and real-time monitoring capabilities, all integrated into wearable technology. Covalent conjugation of antibodies to nanoparticles improves bioactivity, driving innovations in drug targeting. The integration of microfluidics with sensor technologies and artificial intelligence facilitates real-time feedback and autonomous adaptation in drug delivery systems. Key challenges, such as droplet polydispersity and fluidic handling, along with future directions focusing on scalability and reliability, are essential considerations in advancing microfluidics for personalized drug delivery.

中文翻译：

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用于个性化药物输送的微流控

本综述强调了微流体技术对个性化药物输送的变革性影响。微流控解决了传统药物合成中的问题，为纳米颗粒制造提供了精确控制和可扩展性，微流控平台显示出巨大的多功能性潜力，提供针对患者的给药和实时监测功能，所有这些都集成到可穿戴技术中。抗体与纳米颗粒的共价结合提高了生物活性，推动了药物靶向的创新。微流体与传感器技术和人工智能的集成促进了药物输送系统的实时反馈和自主适应。液滴多分散性和流体处理等关键挑战，以及关注可扩展性和可靠性的未来方向，是推进微流体个性化药物输送的重要考虑因素。