In 2021, the National Institute for Health and Care Excellence produced an evidence-based guideline on the diagnosis and management of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), a disabling long-term condition of unknown cause. The guideline provides clear support for people living with ME/CFS, their families and carers, and for clinicians. A recent opinion piece published in the journal suggested that there were anomalies in the processing and interpretation of the evidence when developing the guideline and proposed eight areas where these anomalies were thought to have occurred. We outline how these opinions are based on a misreading or misunderstanding of the guideline process or the guideline, which provides a balanced and reasoned approach to the diagnosis and management of this challenging condition.

中文翻译：

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关于 ME/CFS 的 NICE 指南：基于对证据的彻底审查的有力建议

2021 年，国家健康与护理卓越研究所针对肌痛性脑脊髓炎/慢性疲劳综合征 (ME/CFS)（一种原因不明的长期致残疾病）的诊断和治疗制定了循证指南。该指南为 ME/CFS 患者、他们的家人和护理人员以及临床医生提供了明确的支持。该杂志最近发表的一篇评论文章指出，在制定指南时，证据的处理和解释存在异常，并提出了被认为发生这些异常的八个领域。我们概述了这些意见是如何基于对指南流程或指南的误读或误解，这为诊断和管理这种具有挑战性的疾病提供了平衡且合理的方法。