Efficacy and safety of tirzepatide, GLP-1 receptor agonists, and other weight loss drugs in overweight and obesity: a network meta-analysis,Obesity

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Efficacy and safety of tirzepatide, GLP-1 receptor agonists, and other weight loss drugs in overweight and obesity: a network meta-analysis
Obesity ( IF 6.9 ) Pub Date : 2024-02-27 , DOI: 10.1002/oby.24002
Xin‐Hui Pan ₁ , Bryan Tan ₁ , Yip Han Chin ₂ , Ethan Cheng Zhe Lee ₃ , Gwyneth Kong ₂ , Bryan Chong ₁ , Martin Kueh ₄ , Chin Meng Khoo _{1,

5} , Anurag Mehta ₆ , Priyanka Majety ₇ , Gowtham R. Grandhi ₆ , Georgios K. Dimitriadis _{8,

9} , Roger Foo _{1,

10} , Nicholas W. S. Chew _{1,

10} , Carel W. Le Roux ₁₁ , Mamas A. Mamas _{12,

13} , Mark Y. Chan _{1,

10}

Affiliation

Yong Loo Lin School of Medicine National University of Singapore Singapore
Ministry of Health Holdings Ministry of Health Singapore
Lee Kong Chian School of Medicine Nanyang Technological University Singapore
Royal College of Surgeons in Ireland & University College Dublin Malaysia Campus George Town Malaysia
Department of Endocrinology National University Hospital Singapore
VCU Health Pauley Heart Center, Division of Cardiology, Department of Internal Medicine Virginia Commonwealth University Richmond Virginia USA
Department of Endocrinology, Diabetes and Metabolism Virginia Commonwealth University Health Richmond Virginia USA
Faculty of Life Sciences and Medicine School of Life Course Sciences, King's College London London UK
Department of Endocrinology King's College Hospital NHS Foundation Trust, Denmark Hill London UK
Department of Cardiology National University Heart Centre Singapore
Diabetes Complications Research Centre University College Dublin Dublin Ireland
Keele Cardiovascular Research Group, Centre for Prognosis Research Keele University Keele UK
Department of Cardiology Royal Stoke University Hospital Stoke‐on‐Trent UK

This network meta-analysis evaluates the efficacy and safety of tirzepatide compared to glucagon-like peptide-1 receptor agonists (GLP-1 RA) and other weight loss drugs in the treatment of overweight and obesity.

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