Background and Hypothesis Longer duration of untreated psychosis (DUP) predicts worse outcomes in First Episode Psychosis (FEP). Searching online represents one of the first proactive step toward treatment initiation for many, yet few studies have informed how best to support FEP youth as they engage in early online help-seeking steps to care. Study Design Using a stepped-wedge randomized design, this project evaluated the effectiveness of a digital marketing campaign at reducing DUP and raising rates of referrals to FEP services by proactively targeting and engaging prospective patients and their adult allies online. Study Results Throughout the 18-month campaign, 41 372 individuals visited our website, and 371 advanced to remote clinical assessment (median age = 24.4), including 53 allies and 318 youth. Among those assessed (n = 371), 53 individuals (14.3%) reported symptoms consistent with psychotic spectrum disorders (62.2% female, mean age 20.7 years) including 39 (10.5%) reporting symptoms consistent with either Clinical High Risk (ie, attenuated psychotic symptoms; n = 26) or FEP (n = 13). Among those with either suspected CHR or FEP (n = 39), 20 (51.3%) successfully connected with care. The campaign did not result in significant differences in DUP. Conclusion This study highlights the potential to leverage digital media to help identify and engage youth with early psychosis online. However, despite its potential, online education and professional support alone are not yet sufficient to expedite treatment initiation and reduce DUP.

中文翻译：

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检查数字媒体活动在减少纽约州未经治疗的精神病持续时间方面的有效性：阶梯楔形随机对照试验的结果

背景和假设 未经治疗的精神病 (DUP) 持续时间越长，预示首发精神病 (FEP) 的结果越差。对许多人来说，在线搜索是开始治疗的第一步，但很少有研究表明如何最好地支持 FEP 青少年，因为他们参与早期在线寻求帮助的护理步骤。研究设计 该项目采用阶梯式楔形随机设计，评估了数字营销活动通过主动瞄准和吸引潜在患者及其成年盟友在线来减少 DUP 和提高 FEP 服务转诊率的有效性。研究结果 在整个 18 个月的活动中，有 41 372 人访问了我们的网站，371 人进入了远程临床评估（中位年龄 = 24.4 岁），其中包括 53 名盟友和 318 名青少年。在接受评估的人 (n = 371) 中，53 人 (14.3%) 报告了与精神谱系障碍一致的症状（62.2% 为女性，平均年龄 20.7 岁），其中 39 人 (10.5%) 报告了与临床高风险（即减弱）一致的症状。精神病症状；n = 26) 或 FEP (n = 13)。在疑似 CHR 或 FEP 的患者 (n = 39) 中，20 人 (51.3%) 成功与护理联系。该活动并未导致 DUP 出现显着差异。结论 这项研究强调了利用数字媒体帮助在线识别和吸引患有早期精神病的青少年的潜力。然而，尽管具有潜力，但仅在线教育和专业支持还不足以加快治疗启动和减少 DUP。