Lactate/GPR81 recruits regulatory T cells by modulating CX3CL1 to promote immune resistance in a highly glycolytic gastric cancer,OncoImmunology

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Lactate/GPR81 recruits regulatory T cells by modulating CX3CL1 to promote immune resistance in a highly glycolytic gastric cancer
OncoImmunology ( IF 7.2 ) Pub Date : 2024-02-26 , DOI: 10.1080/2162402x.2024.2320951
Jin Su _{1,

2} , Xinyuan Mao ₁ , Lingzhi Wang ₁ , Zhian Chen ₁ , Weisheng Wang ₁ , Cuiyin Zhao ₁ , Guoxin Li ₁ , Weihong Guo ₁ , Yanfeng Hu ₁

Affiliation

Lactate plays an important role in shaping immune tolerance in tumor microenvironment (TME) and correlates with poor prognosis in various solid tumors. Overcoming the immune resistance in an acidic...

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