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COVID-19 vaccination, infection, and symptoms among cancer survivors in the United States
Journal of the National Cancer Institute ( IF 9.9 ) Pub Date : 2024-02-24 , DOI: 10.1093/jnci/djae029
Nuo Nova Yang 1 , Jingxuan Zhao 1 , Zhiyuan Zheng 1 , K Robin Yabroff 1 , Xuesong Han 1
Affiliation  

The experiences of cancer survivors with the COVID-19 pandemic in the United States during 2021 and 2022, when vaccinations became widely available, are largely undocumented. Using nationally representative survey data in 2021 and 2022, we found that compared with adults without a cancer history, cancer survivors were more likely to have at least 2 COVID-19 vaccines (2021: 66.6% vs 62.3%, P = .003; 2022: 77.0% vs 72.4%, P < .001) and as likely to have a COVID-19 infection history (2021: 14.1% vs 14.2%, P = .93; 2022: 39.9% vs 39.3%, P = .55) but, once infected, were more likely to develop moderate to severe symptoms (2021: 62.5% vs 54.2%, P = .02; 54.5% vs 61.3%; P = .13). Among cancer survivors, younger age, lower educational attainment, lack of health insurance, and more comorbidities were statistically significantly associated with lower vaccination rates (P < .001). Among infected cancer survivors, being female and younger were associated with higher likelihood of developing moderate to severe symptoms (P < .001). Our findings suggest tailored efforts to prevent and control COVID-19 infections for cancer survivors.

中文翻译:


美国癌症幸存者中的 COVID-19 疫苗接种、感染和症状



2021 年和 2022 年疫苗接种广泛普及期间,美国癌症幸存者在 COVID-19 大流行中的经历基本上没有记录。使用 2021 年和 2022 年全国代表性调查数据,我们发现与没有癌症病史的成年人相比,癌症幸存者更有可能接种至少 2 种 COVID-19 疫苗(2021 年:66.6% vs 62.3%,P = .003;2022 年) :77.0% vs 72.4%,P < .001)并且可能有 COVID-19 感染史(2021 年:14.1% vs 14.2%,P = .93;2022 年:39.9% vs 39.3%,P = .55 )但一旦感染,更有可能出现中度至重度症状(2021 年:62.5% vs 54.2%,P = .02;54.5% vs 61.3%;P = .13)。在癌症幸存者中,年龄较小、教育程度较低、缺乏健康保险和更多合并症与较低的疫苗接种率在统计上显着相关 (P < .001)。在受感染的癌症幸存者中,女性和年轻女性出现中度至重度症状的可能性较高(P < .001)。我们的研究结果表明,应采取针对性措施来预防和控制癌症幸存者的 COVID-19 感染。
更新日期:2024-02-24
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