The present study focused on the ability to combine magnetic NMs to enable the use of their synergistic additives and new properties for the development of different sensing systems in various fields. A novel kind of integration of magnetic NPs in the sensing systems results in its significant improvement of sensitivity, limit of detection and stability. The applicability of NPs as colourimetric sensors, biosensors and sorbents is inevitable. Accordingly, the SPIONs used for drug delivery in vivo sized from 10 to 200 nm make them able to escape from attacks macrophages of the immune system part (>200 nm) and could avoid renal excretion (<10 nm). A novel FeO@Pt NPs as a paper-based colourimetric sensor has determined LOD for glucose was 0.36 μM in a human sample. Moreover, PPY-based biosensor gave valid glucose evaluation in fruit juices and non-alcoholic drinks with LOD of 26.9 μM. Chemical approaches are the most used, even 90%. Characterization of nanostructures is done mainly by transmission electron microscopy, thermogravimetric analysis, X-ray diffraction, Fourier transform infrared spectroscopy and scanning electron microscopy. For the production and commercialization of the MNPs, controlled size, standardized, cost-effective and controlled synthesis methods are required. The focus on the green character of magnetic NMs, their synthesis and green properties would advance future studies, particularly for the development of non-toxic NMs for their safer further application.

中文翻译：

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用于增强横向化学和生物分析应用的磁性多功能纳米材料——综述

目前的研究重点是结合磁性纳米材料的能力，以利用其协同添加剂和新特性来开发各个领域的不同传感系统。传感系统中磁性纳米颗粒的一种新型集成显着提高了灵敏度、检测限和稳定性。纳米颗粒作为比色传感器、生物传感器和吸附剂的应用是不可避免的。因此，用于体内药物递送的SPIONs尺寸为10至200 nm，使其能够逃避免疫系统部分巨噬细胞（>200 nm）的攻击，并可以避免肾脏排泄（<10 nm）。作为纸基比色传感器的新型 FeO@Pt NP 已确定人体样本中葡萄糖的 LOD 为 0.36 μM。此外，基于 PPY 的生物传感器可以有效评估果汁和非酒精饮料中的葡萄糖，LOD 为 26.9 μM。化学方法使用最多，甚至占 90%。纳米结构的表征主要通过透射电子显微镜、热重分析、X射线衍射、傅里叶变换红外光谱和扫描电子显微镜来完成。对于 MNP 的生产和商业化，需要控制尺寸、标准化、具有成本效益和受控的合成方法。对磁性纳米材料的绿色特性、其合成和绿色特性的关注将推动未来的研究，特别是开发无毒纳米材料以使其更安全的进一步应用。