Cortical Thickness Patterns of Cognitive Impairment Phenotypes in Drug-Resistant Temporal Lobe Epilepsy,Annals of Neurology

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Cortical Thickness Patterns of Cognitive Impairment Phenotypes in Drug-Resistant Temporal Lobe Epilepsy
Annals of Neurology ( IF 11.2 ) Pub Date : 2024-02-23 , DOI: 10.1002/ana.26893
Gadi Miron _{1,

2,

3,

4} , Paul Manuel Müller _{1,

4,

5} , Louisa Hohmann _{2,

3} , Frank Oltmanns ₃ , Martin Holtkamp _{2,

3} , Christian Meisel _{1,

4,

5,

6,

7} , Claudia Chien _{8,

9,

10}

Affiliation

Computational Neurology, Department of Neurology Charité–Universitätsmedizin Berlin Berlin Germany
Epilepsy Center Berlin‐Brandenburg, Department of Neurology Charité–Universitätsmedizin Berlin Berlin Germany
Epilepsy Center Berlin‐Brandenburg Institute for Diagnostics of Epilepsy Berlin Germany
Berlin Institute of Health Berlin Germany
NeuroCure Cluster of Excellence Charité–Universitätsmedizin Berlin Berlin Germany
Bernstein Center for Computational Neuroscience Berlin Germany
Center for Stroke Research Berlin Berlin Germany
Experimental Clinical and Research Center Charité–Universitätsmedizin Berlin Berlin Germany
Neuroscience Clinical Research Center Charité–Universitätsmedizin Berlin Berlin Germany
Department of Psychiatry and Neuroscience Charité–Universitätsmedizin Berlin Berlin Germany

In temporal lobe epilepsy (TLE), a taxonomy classifying patients into 3 cognitive phenotypes has been adopted: minimally, focally, or multidomain cognitively impaired (CI). We examined gray matter (GM) thickness patterns of cognitive phenotypes in drug-resistant TLE and assessed potential use for predicting postsurgical cognitive outcomes.

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