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Reagent- and solvent-controlled product divergence in the reaction of trifluorodiazoethane with arylidene-1,3-indanediones
Journal of Fluorine Chemistry ( IF 1.9 ) Pub Date : 2024-02-06 , DOI: 10.1016/j.jfluchem.2024.110256
Mumtaz Ahmad , Lubina Fatma , Ruchir Kant , Kishor Mohanan

[Display omitted] An interesting product divergence in the reaction of trifluorodiazoethane with arylidene-1,3-indanediones is reported. The reaction conducted using 10 mol% of silver carbonate afforded trifluoromethylspiropyrazolines, while with excess of cesium fluoride in methanol, the cycloaddition was followed by nucleophilic ring opening of the spiropyrazoline to afford trifluoromethylated -carbomethoxybenzoylpyrazolines.

中文翻译:

三氟重氮乙烷与亚芳基-1,3-茚满二酮反应中试剂和溶剂控制的产物分歧

[显示省略] 报道了三氟重氮乙烷与亚芳基-1,3-茚满二酮反应中有趣的产物分歧。使用10mol%的碳酸银进行反应,得到三氟甲基螺吡唑啉,而在甲醇中使用过量的氟化铯,环加成之后螺吡唑啉的亲核开环,得到三氟甲基化的-甲氧基苯甲酰基吡唑啉。
更新日期:2024-02-06
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