当前位置: X-MOL 学术Dev. Cell › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Determining the potency of primordial germ cells by injection into early mouse embryos
Developmental Cell ( IF 11.8 ) Pub Date : 2024-02-14 , DOI: 10.1016/j.devcel.2024.01.022
Lessly P. Sepulveda-Rincon , Yi-Fang Wang , Chad Whilding , Benjamin Moyon , Obah A. Ojarikre , Valdone Maciulyte , Nobuhiko Hamazaki , Katsuhiko Hayashi , James M.A. Turner , Harry G. Leitch

Sepulveda-Rincon et al. present a detailed investigation of the potency of primordial germ cells (PGCs). Following injection into early mouse embryos, PGCs can display properties akin to naive pluripotent cells, but they do not functionally contribute to later embryogenesis, supporting the notion that PGCs exhibit a latent form of pluripotency.

中文翻译:

通过注射到早期小鼠胚胎中确定原始生殖细胞的效力

塞普尔韦达-林孔等人。对原始生殖细胞(PGC)的效力进行了详细研究。注射到早期小鼠胚胎中后,PGC 可以表现出类似于幼稚多能细胞的特性,但它们在功能上对后来的胚胎发生没有贡献,这支持了 PGC 表现出潜在形式的多能性的观点。
更新日期:2024-02-14
down
wechat
bug