Wu et al. use scRNA-seq to evaluate how Wnt signaling dose affects derivation of cell types from pluripotency. They build a computational model to identify a gene set predictive of cardiomyocyte differentiation and identify a small-molecule Wnt regulator, tranilast, that promotes cardiac differentiation both and .

中文翻译：

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退出多能性期间 Wnt 剂量递增表明曲尼司特是心脏中胚层的调节剂

吴等人。使用 scRNA-seq 评估 Wnt 信号传导剂量如何影响多能性细胞类型的衍生。他们建立了一个计算模型来识别预测心肌细胞分化的基因组，并识别出一种小分子 Wnt 调节剂曲尼司特，它可以促进心脏分化。