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Structural mechanisms of α7 nicotinic receptor allosteric modulation and activation
Cell ( IF 64.5 ) Pub Date : 2024-02-20 , DOI: 10.1016/j.cell.2024.01.032
Sean M. Burke , Mariia Avstrikova , Colleen M. Noviello , Nuriya Mukhtasimova , Jean-Pierre Changeux , Ganesh A. Thakur , Steven M. Sine , Marco Cecchini , Ryan E. Hibbs

Structural interrogation of α7 nicotinic receptor positive modulation clarifies class-specific differences, reveals unique properties of the α7 subtype, and supports a conserved potentiation mechanism among related ion channels.

中文翻译:

α7烟碱受体变构调节和激活的结构机制

对 α7 烟碱受体正调节的结构研究阐明了类别特异性差异,揭示了 α7 亚型的独特性质,并支持相关离子通道之间保守的增强机制。
更新日期:2024-02-20
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