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Helical BODIPY Dyes as Heavy-Atom-Free Triplet Photosensitizers for Photodynamic Therapy of Cancer
ChemMedChem ( IF 3.4 ) Pub Date : 2024-02-15 , DOI: 10.1002/cmdc.202400041
Soumyaditya Mula 1 , Mrunesh Koli 2
Affiliation  

The concept of structural helicity to enhance the triplet conversion of BODIPY dyes is discussed with reported helical BODIPYs. These dyes have high triplet yields, long triplet lifetimes and are capable of generating high singlet oxygens even in hypoxia condition. Potential applications of these helical BODIPYs as heavy-atom-free triplet photosensitizers for photodynamic therapy of cancer is also reviewed.

中文翻译:

螺旋 BODIPY 染料作为无重原子三重态光敏剂用于癌症光动力治疗

与已报道的螺旋 BODIPY 一起讨论了增强 BODIPY 染料三重态转化的结构螺旋度概念。这些染料具有高三线态产率、长三线态寿命,并且即使在缺氧条件下也能够产生高单线态氧。还回顾了这些螺旋 BODIPY 作为无重原子三重态光敏剂在癌症光动力治疗中的潜在应用。
更新日期:2024-02-15
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