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Glial lipid droplets resolve ROS during sleep
Nature Neuroscience ( IF 25.0 ) Pub Date : 2024-02-15 , DOI: 10.1038/s41593-023-01546-7
Lindsey D. Goodman , Matthew J. Moulton , Hugo J. Bellen

The Sehgal lab presents data showing that the non-cell autonomous pathway of glial lipid droplet formation occurs during sleep and helps to resolve neuronal reactive oxygen species (ROS). This promotes neuronal function after an active day. Hence, this pathway has an important physiological function beyond its previously described role in ROS-associated diseases, including Alzheimer’s disease.

中文翻译:

神经胶质脂滴在睡眠期间分解ROS

Sehgal 实验室提供的数据表明,神经胶质脂滴形成的非细胞自主途径发生在睡眠期间,有助于分解神经元活性氧 (ROS)。这可以在活跃的一天后促进神经元功能。因此,除了之前描述的 ROS 相关疾病(包括阿尔茨海默病)中的作用之外,该途径还具有重要的生理功能。
更新日期:2024-02-15
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