Evaluating appetite/satiety hormones and eating behaviours as predictors of weight loss maintenance with GLP-1RA therapy in adolescents with severe obesity,Pediatric Obesity

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Evaluating appetite/satiety hormones and eating behaviours as predictors of weight loss maintenance with GLP-1RA therapy in adolescents with severe obesity
Pediatric Obesity ( IF 3.8 ) Pub Date : 2024-02-09 , DOI: 10.1111/ijpo.13105
Megan O. Bensignor _{1,

2} , Aaron S. Kelly _{1,

2} , Alicia Kunin‐Batson _{1,

2} , Claudia K. Fox _{1,

2} , Rebecca Freese ₃ , Justin Clark ₄ , Kyle D. Rudser _{2,

3,

4} , Eric M. Bomberg _{1,

2} , Justin Ryder _{5,

6} , Amy C. Gross _{1,

2}

Affiliation

Whilst glucagon-like peptide-1 receptor agonists (GLP1-RAs) are effective for treating adolescent obesity, weight loss maintenance (WLM; preventing weight regain) remains a challenge. Our goal was to investigate appetite/satiety hormones and eating behaviours that may predict WLM with exenatide (a GLP1-RA) versus placebo in adolescents with severe obesity.

中文翻译：

评估食欲/饱腹感激素和饮食行为作为重度肥胖青少年 GLP-1RA 治疗维持减肥的预测因子

虽然胰高血糖素样肽 1 受体激动剂 (GLP1-RA) 可有效治疗青少年肥胖，但维持减肥（WLM；防止体重反弹）仍然是一个挑战。我们的目标是调查食欲/饱腹感激素和饮食行为，这些激素和饮食行为可以预测艾塞那肽（GLP1-RA）与安慰剂在严重肥胖青少年中的 WLM。

更新日期：2024-02-09

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