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mtDNA caught in the act again
Nature Cell Biology ( IF 21.3 ) Pub Date : 2024-02-08 , DOI: 10.1038/s41556-024-01345-7 Kate McArthur , Benjamin T. Kile
Nature Cell Biology ( IF 21.3 ) Pub Date : 2024-02-08 , DOI: 10.1038/s41556-024-01345-7 Kate McArthur , Benjamin T. Kile
Despite a growing understanding of the immunostimulatory properties of mitochondrial DNA (mtDNA), little is known about how and why mtDNA escapes its mitochondrial confines. A study now describes an endosomal trafficking pathway that facilitates mtDNA egress and provides an additional mechanism of mtDNA release in vitro.
更新日期:2024-02-09